Table 3 Adjusted MMSE slopes (points/ year) after Alzheimer’s disease diagnosis comparing those who received C-ACEIs and those who received NC-ACEIs
MMSE slopeReceived C-ACEIsReceived NC-ACEIsMMSE slope difference (MMSE per year)P for group difference
First MMSE slope 0–9 months0.72 (0.89 to 0.55)−0.61 (−0.21 to −1.02)1.33 (0.25 to 1.41)0.028
Second MMSE slope 9–36 months−0.81 (−1.17 to −0.45)−0.63 (−1.36 to 0.10)−0.18 (−1.50 to −1.14)0.531
  • MMSE, Mini-Mental State Examination; C-ACEIs, centrally acting angiotensin converting enzyme inhibitors; NC-ACEIs, non-centrally acting angiotensin converting enzyme inhibitors.