Table 1 Patient baseline characteristics
Patients with schizophreniaPatients with bipolar I disorder
CharacteristicPlacebo n=1155 mg n=11610 mg n=113Placebo n=1055 mg n=10410 mg n=105
Mean (s.d.) age, years48.3 (9.5)43.2 (10.2)42.1 (9.8)40.6 (9.8)41.2 (9.6)40.5 (9.8)
Mean (s.d.) time since diagnosis, years18.8 (10.3)16.5 (10.8)18.2 (10.0)12.0 (10.1)12.8 (8.9)11.7 (9.1)
Mean (s.d.) duration of current agitation episode, days6.9 (9.2)6.1 (7.5)7.6 (11.5)14.2 (21.5)16.0 (32.4)9.7 (10.2)
Mean (s.d.) number of previous hospitalisations9.6 (9.0)9.2 (12.2)9.7 (11.3)5.9 (6.6)5.5 (6.6)5.0 (6.4)
Male, %707775534551
Smokers, %788186747673
Mean (s.d.) baseline score on items of the PANSS-EC scalea
 Poor impulse control3.3 (0.6)3.4 (0.8)3.4 (0.6)3.3 (0.9)3.4 (0.8)3.3 (0.8)
 Tension4.0 (0.6)4.0 (0.6)4.0 (0.7)4.0 (0.9)4.1 (0.7)4.2 (0.6)
 Hostility3.2 (0.8)3.3 (0.8)3.3 (0.8)3.5 (1.0)3.3 (1.0)3.2 (0.9)
 Uncooperativeness3.0 (0.8)3.2 (0.8)3.2 (0.9)2.9 (0.9)2.8 (0.8)2.7 (1.0)
 Excitement3.7 (0.7)3.9 (0.8)3.7 (0.7)4.0 (0.9)3.9 (0.7)3.9 (0.7)
  • PANSS-EC, Positive and Negative Syndrome Scale – Excited Component.

  • a Each of the five individual items is rated on a scale of 1 (absent) to 7 (extreme).